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New approaches to blood sugar regulation with collagen peptides

Rousselot has been a leader in the development of collagen solutions for over 130 years and specialises in further researching and exploiting the multiple health benefits of collagen peptides. Collagen is known for its structural function in skin, bones and joints - but its positive effects on health go far beyond that.

With the development of an extensive library of specialised collagen peptides, Rousselot has the ability to offer targeted health benefits. A standout innovation from this research is Nextida GC, a specialised collagen peptide formulation that aims to stabilise post-meal blood sugar spikes and provide an effective solution for blood sugar management.


Nextida GC: Effective blood sugar regulation after meals

After consuming meals, especially those high in sugar and carbohydrates, there is a rapid rise in blood sugar. This rise often leads to an energy high, which is followed by an abrupt ‘sugar crash’ that can result in fatigue, mood swings and sugar cravings. These fluctuations have a negative impact on general well-being and can affect long-term health.

Nextida GC addresses this problem by supporting the body's natural ability to regulate blood sugar. It promotes the release of the incretin hormones GLP-1 and GIP, which play an essential role in blood sugar control. These hormones improve insulin production and delay gastric emptying, which reduces the rise in blood sugar after meals while promoting a long-lasting feeling of satiety.


Scientific validation of Nextida GC

Through extensive in vitro testing of the collagen peptide library, Rousselot identified Nextida GC as a promising candidate to increase GLP-1 release. Preclinical tests in mice confirmed that Nextida GC significantly increases GLP-1 levels and thus enables improved blood glucose regulation.


Influence of Nextida GC on natural GLP-1 secretion



Nextida GC reduced glucose peaks in normoglycaemic (A) and prediabetic mice (B) after glucose loading


Key results: In vitro tests showed that Nextida GC significantly increased GLP-1 secretion in enteroendocrine cell models. Preclinical studies in normal and prediabetic mice demonstrated that Nextida GC at a dose of 4 g/kg significantly increased GLP-1 levels and thus improved glycaemic management. The first clinical study with Nextida GC showed that a dose of 5 or 10 grams significantly reduced blood glucose levels after a meal.

These results support the use of Nextida GC for targeted blood glucose regulation. The scientific background of Nextida GC is based on the incretin effect, which plays a key role in the regulation of blood glucose, in particular by promoting GLP-1 release. In addition, Nextida GC reduced the post-meal blood glucose spike by an average of 42% at a dose of 5g. Clinical and preclinical studies demonstrate the positive effect of Nextida GC on blood glucose regulation. These results demonstrate the efficacy of Nextida GC in blood glucose regulation, especially in people with metabolic disorders such as prediabetes.



Oral supplementation with 5 or 10 grams of Nextida GC


Sustainability and high quality

Nextida GC is made from sustainably sourced collagen and fulfils both EU and US standards for safety and quality. The ingredient is characterised by excellent solubility in hot and cold water and has excellent sensory properties as well as high stability in terms of temperature, pH and shelf life. These properties make Nextida GC an ideal choice for manufacturers of dietary supplements and functional foods.

Extensive preclinical and clinical studies have scientifically proven the efficacy of Nextida GC in blood glucose regulation. Collagen peptides are a natural, well-tolerated and safe alternative to other blood glucose regulation strategies, without undesirable side effects. Especially health-conscious consumers who want to regulate their blood glucose levels in a natural and sustainable way will benefit from this solution.


Further information and materials

For detailed information on Nextida GC, a short video and a webinar, please visit Nextida GC Rousselot. Contact us for further details or enquiries.

Below you can download two brochures from Nextida GC:


Rousselot
Science brochure Marketing brochure



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